{"id":24490,"date":"2024-12-08T19:57:14","date_gmt":"2024-12-08T17:57:14","guid":{"rendered":"https:\/\/oewf.org\/?p=24490"},"modified":"2024-12-17T10:47:58","modified_gmt":"2024-12-17T08:47:58","slug":"amadee-24-science-series-telomere-length-dynamics-in-analog-astronauts-genes4mars","status":"publish","type":"post","link":"https:\/\/oewf.org\/en\/2024\/12\/amadee-24-science-series-telomere-length-dynamics-in-analog-astronauts-genes4mars\/","title":{"rendered":"AMADEE-24 Science Series: Telomere Length Dynamics in Analog Astronauts (Genes4Mars)"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\">Telomeres are essential structures located at the ends of linear chromosomes in eukaryotes. In humans, they consist of short TTAGGG repeats and are associated with various proteins [ref]. They play a critical role in maintaining the structural integrity of chromosomes and regulating genome replication and stability. The shortening of telomeres is linked to cellular senescence and aging.<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure data-wp-context=\"{&quot;imageId&quot;:&quot;6a5a999e1fad2&quot;}\" data-wp-interactive=\"core\/image\" data-wp-key=\"6a5a999e1fad2\" class=\"aligncenter size-full wp-lightbox-container\"><img loading=\"lazy\" decoding=\"async\" width=\"2048\" height=\"1536\" data-wp-class--hide=\"state.isContentHidden\" data-wp-class--show=\"state.isContentVisible\" data-wp-init=\"callbacks.setButtonStyles\" data-wp-on--click=\"actions.showLightbox\" data-wp-on--load=\"callbacks.setButtonStyles\" data-wp-on--pointerdown=\"actions.preloadImage\" data-wp-on--pointerenter=\"actions.preloadImageWithDelay\" data-wp-on--pointerleave=\"actions.cancelPreload\" data-wp-on-window--resize=\"callbacks.setButtonStyles\" src=\"https:\/\/oewf.org\/wp-content\/uploads\/2024\/12\/ebb256ca-140f-484a-8db3-6cb9ed7847e0.jpg\" alt=\"Arsen Arakelyan presented &quot;Genes4Mars&quot; during the AMADEE-24 Science Workshop (c) OeWF\" class=\"wp-image-24499\" srcset=\"https:\/\/oewf.org\/wp-content\/uploads\/2024\/12\/ebb256ca-140f-484a-8db3-6cb9ed7847e0.jpg 2048w, https:\/\/oewf.org\/wp-content\/uploads\/2024\/12\/ebb256ca-140f-484a-8db3-6cb9ed7847e0-300x225.jpg 300w, https:\/\/oewf.org\/wp-content\/uploads\/2024\/12\/ebb256ca-140f-484a-8db3-6cb9ed7847e0-600x450.jpg 600w, https:\/\/oewf.org\/wp-content\/uploads\/2024\/12\/ebb256ca-140f-484a-8db3-6cb9ed7847e0-768x576.jpg 768w, https:\/\/oewf.org\/wp-content\/uploads\/2024\/12\/ebb256ca-140f-484a-8db3-6cb9ed7847e0-1536x1152.jpg 1536w\" sizes=\"auto, (max-width: 2048px) 100vw, 2048px\" \/><button\n\t\t\tclass=\"lightbox-trigger\"\n\t\t\ttype=\"button\"\n\t\t\taria-haspopup=\"dialog\"\n\t\t\tdata-wp-bind--aria-label=\"state.thisImage.triggerButtonAriaLabel\"\n\t\t\tdata-wp-init=\"callbacks.initTriggerButton\"\n\t\t\tdata-wp-on--click=\"actions.showLightbox\"\n\t\t\tdata-wp-style--right=\"state.thisImage.buttonRight\"\n\t\t\tdata-wp-style--top=\"state.thisImage.buttonTop\"\n\t\t>\n\t\t\t<svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"12\" height=\"12\" fill=\"none\" viewBox=\"0 0 12 12\">\n\t\t\t\t<path fill=\"#fff\" d=\"M2 0a2 2 0 0 0-2 2v2h1.5V2a.5.5 0 0 1 .5-.5h2V0H2Zm2 10.5H2a.5.5 0 0 1-.5-.5V8H0v2a2 2 0 0 0 2 2h2v-1.5ZM8 12v-1.5h2a.5.5 0 0 0 .5-.5V8H12v2a2 2 0 0 1-2 2H8Zm2-12a2 2 0 0 1 2 2v2h-1.5V2a.5.5 0 0 0-.5-.5H8V0h2Z\" \/>\n\t\t\t<\/svg>\n\t\t<\/button><figcaption class=\"wp-element-caption\"><em>Arsen Arakelyan presented <em>&#8220;Genes4Mars&#8221; during the AMADEE-24 Science Workshop (c) OeWF<\/em><\/em><\/figcaption><\/figure>\n<\/div>\n\n\n<p class=\"wp-block-paragraph\">Telomeres have been shown to respond to various stressors associated with space travel. It has been observed that astronauts at the International Space Station (ISS) exhibited changes in telomere length during their missions and upon returning to Earth. However, the specific effectsof individual stressors, such as microgravity, ionizing radiation, and isolation, still need to be understood.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">This study aimed to evaluate the effects of isolation and extravehicular activity (EVA) on telomere length during the AMADEE-24 Mars simulation.<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure data-wp-context=\"{&quot;imageId&quot;:&quot;6a5a999e204e5&quot;}\" data-wp-interactive=\"core\/image\" data-wp-key=\"6a5a999e204e5\" class=\"aligncenter size-full wp-lightbox-container\"><img loading=\"lazy\" decoding=\"async\" width=\"1600\" height=\"900\" data-wp-class--hide=\"state.isContentHidden\" data-wp-class--show=\"state.isContentVisible\" data-wp-init=\"callbacks.setButtonStyles\" data-wp-on--click=\"actions.showLightbox\" data-wp-on--load=\"callbacks.setButtonStyles\" data-wp-on--pointerdown=\"actions.preloadImage\" data-wp-on--pointerenter=\"actions.preloadImageWithDelay\" data-wp-on--pointerleave=\"actions.cancelPreload\" data-wp-on-window--resize=\"callbacks.setButtonStyles\" src=\"https:\/\/oewf.org\/wp-content\/uploads\/2024\/12\/65e05188-8019-4ec1-8c80-d7879e63a215.jpg\" alt=\"&quot;Genes4Mars&quot; presentation at the AMADEE-24 Science Workshop, here telomere length dynamics at individual levels (c) OeWF\" class=\"wp-image-24497\" srcset=\"https:\/\/oewf.org\/wp-content\/uploads\/2024\/12\/65e05188-8019-4ec1-8c80-d7879e63a215.jpg 1600w, https:\/\/oewf.org\/wp-content\/uploads\/2024\/12\/65e05188-8019-4ec1-8c80-d7879e63a215-300x169.jpg 300w, https:\/\/oewf.org\/wp-content\/uploads\/2024\/12\/65e05188-8019-4ec1-8c80-d7879e63a215-600x338.jpg 600w, https:\/\/oewf.org\/wp-content\/uploads\/2024\/12\/65e05188-8019-4ec1-8c80-d7879e63a215-768x432.jpg 768w, https:\/\/oewf.org\/wp-content\/uploads\/2024\/12\/65e05188-8019-4ec1-8c80-d7879e63a215-1536x864.jpg 1536w\" sizes=\"auto, (max-width: 1600px) 100vw, 1600px\" \/><button\n\t\t\tclass=\"lightbox-trigger\"\n\t\t\ttype=\"button\"\n\t\t\taria-haspopup=\"dialog\"\n\t\t\tdata-wp-bind--aria-label=\"state.thisImage.triggerButtonAriaLabel\"\n\t\t\tdata-wp-init=\"callbacks.initTriggerButton\"\n\t\t\tdata-wp-on--click=\"actions.showLightbox\"\n\t\t\tdata-wp-style--right=\"state.thisImage.buttonRight\"\n\t\t\tdata-wp-style--top=\"state.thisImage.buttonTop\"\n\t\t>\n\t\t\t<svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"12\" height=\"12\" fill=\"none\" viewBox=\"0 0 12 12\">\n\t\t\t\t<path fill=\"#fff\" d=\"M2 0a2 2 0 0 0-2 2v2h1.5V2a.5.5 0 0 1 .5-.5h2V0H2Zm2 10.5H2a.5.5 0 0 1-.5-.5V8H0v2a2 2 0 0 0 2 2h2v-1.5ZM8 12v-1.5h2a.5.5 0 0 0 .5-.5V8H12v2a2 2 0 0 1-2 2H8Zm2-12a2 2 0 0 1 2 2v2h-1.5V2a.5.5 0 0 0-.5-.5H8V0h2Z\" \/>\n\t\t\t<\/svg>\n\t\t<\/button><figcaption class=\"wp-element-caption\"><em><em>&#8220;Genes4Mars&#8221; presentation at the AMADEE-24 Science Workshop, here telomere length dynamics at individual levels (c) OeWF<\/em><\/em><\/figcaption><\/figure>\n<\/div>\n\n\n<p class=\"wp-block-paragraph\">Six analog astronauts (AAs) participated in the study. Blood samples were collected in K3EDTA tubes before the mission and on days 3, 8, 11, and 15 of isolation. Genomic DNA and total RNA were extracted using the Promega Maxwell RSC automated nucleic acid isolation workstation with corresponding kits. DNA was used to measure telomere length, while RNA was stored for further sequencing library preparation. Relative telomere length (RTL) was measured using quantitative real-time PCR, which determines the ratio of telomeric DNA to a single-copy gene for each sample. The RTL values before isolation were used as a baseline. Differences in RTL at the various time points were assessed using ANOVA with Tukey HSD post hoc tests.<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure data-wp-context=\"{&quot;imageId&quot;:&quot;6a5a999e20cdc&quot;}\" data-wp-interactive=\"core\/image\" data-wp-key=\"6a5a999e20cdc\" class=\"aligncenter size-full wp-lightbox-container\"><img loading=\"lazy\" decoding=\"async\" width=\"1600\" height=\"764\" data-wp-class--hide=\"state.isContentHidden\" data-wp-class--show=\"state.isContentVisible\" data-wp-init=\"callbacks.setButtonStyles\" data-wp-on--click=\"actions.showLightbox\" data-wp-on--load=\"callbacks.setButtonStyles\" data-wp-on--pointerdown=\"actions.preloadImage\" data-wp-on--pointerenter=\"actions.preloadImageWithDelay\" data-wp-on--pointerleave=\"actions.cancelPreload\" data-wp-on-window--resize=\"callbacks.setButtonStyles\" src=\"https:\/\/oewf.org\/wp-content\/uploads\/2024\/12\/Bildschirmfoto-2024-12-02-um-14.57.44.png\" alt=\"Telomere Length Dynamics in Analog Astronauts During the AMADEE-24 Mission. A) Sampling scheme. B) Experimental procedures. c) RTL change throughout the mission.\" class=\"wp-image-24492\" srcset=\"https:\/\/oewf.org\/wp-content\/uploads\/2024\/12\/Bildschirmfoto-2024-12-02-um-14.57.44.png 1600w, https:\/\/oewf.org\/wp-content\/uploads\/2024\/12\/Bildschirmfoto-2024-12-02-um-14.57.44-300x143.png 300w, https:\/\/oewf.org\/wp-content\/uploads\/2024\/12\/Bildschirmfoto-2024-12-02-um-14.57.44-600x287.png 600w, https:\/\/oewf.org\/wp-content\/uploads\/2024\/12\/Bildschirmfoto-2024-12-02-um-14.57.44-768x367.png 768w, https:\/\/oewf.org\/wp-content\/uploads\/2024\/12\/Bildschirmfoto-2024-12-02-um-14.57.44-1536x733.png 1536w\" sizes=\"auto, (max-width: 1600px) 100vw, 1600px\" \/><button\n\t\t\tclass=\"lightbox-trigger\"\n\t\t\ttype=\"button\"\n\t\t\taria-haspopup=\"dialog\"\n\t\t\tdata-wp-bind--aria-label=\"state.thisImage.triggerButtonAriaLabel\"\n\t\t\tdata-wp-init=\"callbacks.initTriggerButton\"\n\t\t\tdata-wp-on--click=\"actions.showLightbox\"\n\t\t\tdata-wp-style--right=\"state.thisImage.buttonRight\"\n\t\t\tdata-wp-style--top=\"state.thisImage.buttonTop\"\n\t\t>\n\t\t\t<svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"12\" height=\"12\" fill=\"none\" viewBox=\"0 0 12 12\">\n\t\t\t\t<path fill=\"#fff\" d=\"M2 0a2 2 0 0 0-2 2v2h1.5V2a.5.5 0 0 1 .5-.5h2V0H2Zm2 10.5H2a.5.5 0 0 1-.5-.5V8H0v2a2 2 0 0 0 2 2h2v-1.5ZM8 12v-1.5h2a.5.5 0 0 0 .5-.5V8H12v2a2 2 0 0 1-2 2H8Zm2-12a2 2 0 0 1 2 2v2h-1.5V2a.5.5 0 0 0-.5-.5H8V0h2Z\" \/>\n\t\t\t<\/svg>\n\t\t<\/button><\/figure>\n<\/div>\n\n\n<p class=\"wp-block-paragraph\">Our results showed a near-significant shortening of telomeres in AAs\u2019 leukocytes during the early days of isolation, compared to baseline. However, RTL began to increase at later time points, approaching baseline values. These findings suggest that the initial days of isolation may lead to immunosenescence and a temporary reduction in immune system activity, which then recoversto normal levels. This indicates that immune-modulating interventions could be beneficial during the early phases of isolation to maintain immune system activity and reduce potential health risks. We would like to thank AMADEE-2024 Analog Astronauts, Flight Planning, Remote Science Support, and GOST team members for their volunteering and support. Funding for the experiment was provided by the Institute of Molecular Biology of the National Academy of Sciences of Armenia.<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure data-wp-context=\"{&quot;imageId&quot;:&quot;6a5a999e2142a&quot;}\" data-wp-interactive=\"core\/image\" data-wp-key=\"6a5a999e2142a\" class=\"aligncenter size-full wp-lightbox-container\"><img loading=\"lazy\" decoding=\"async\" width=\"1599\" height=\"899\" data-wp-class--hide=\"state.isContentHidden\" data-wp-class--show=\"state.isContentVisible\" data-wp-init=\"callbacks.setButtonStyles\" data-wp-on--click=\"actions.showLightbox\" data-wp-on--load=\"callbacks.setButtonStyles\" data-wp-on--pointerdown=\"actions.preloadImage\" data-wp-on--pointerenter=\"actions.preloadImageWithDelay\" data-wp-on--pointerleave=\"actions.cancelPreload\" data-wp-on-window--resize=\"callbacks.setButtonStyles\" src=\"https:\/\/oewf.org\/wp-content\/uploads\/2024\/12\/0c22c299-2a5d-4c63-be19-a2cddac65cd2.jpg\" alt=\"&quot;Genes4Mars&quot; presentation at the AMADEE-24 Science Workshop at Vega Observatory and Haus der Natur in Salzburg (c) OeWF\" class=\"wp-image-24495\" srcset=\"https:\/\/oewf.org\/wp-content\/uploads\/2024\/12\/0c22c299-2a5d-4c63-be19-a2cddac65cd2.jpg 1599w, https:\/\/oewf.org\/wp-content\/uploads\/2024\/12\/0c22c299-2a5d-4c63-be19-a2cddac65cd2-300x169.jpg 300w, https:\/\/oewf.org\/wp-content\/uploads\/2024\/12\/0c22c299-2a5d-4c63-be19-a2cddac65cd2-600x337.jpg 600w, https:\/\/oewf.org\/wp-content\/uploads\/2024\/12\/0c22c299-2a5d-4c63-be19-a2cddac65cd2-768x432.jpg 768w, https:\/\/oewf.org\/wp-content\/uploads\/2024\/12\/0c22c299-2a5d-4c63-be19-a2cddac65cd2-1536x864.jpg 1536w\" sizes=\"auto, (max-width: 1599px) 100vw, 1599px\" \/><button\n\t\t\tclass=\"lightbox-trigger\"\n\t\t\ttype=\"button\"\n\t\t\taria-haspopup=\"dialog\"\n\t\t\tdata-wp-bind--aria-label=\"state.thisImage.triggerButtonAriaLabel\"\n\t\t\tdata-wp-init=\"callbacks.initTriggerButton\"\n\t\t\tdata-wp-on--click=\"actions.showLightbox\"\n\t\t\tdata-wp-style--right=\"state.thisImage.buttonRight\"\n\t\t\tdata-wp-style--top=\"state.thisImage.buttonTop\"\n\t\t>\n\t\t\t<svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"12\" height=\"12\" fill=\"none\" viewBox=\"0 0 12 12\">\n\t\t\t\t<path fill=\"#fff\" d=\"M2 0a2 2 0 0 0-2 2v2h1.5V2a.5.5 0 0 1 .5-.5h2V0H2Zm2 10.5H2a.5.5 0 0 1-.5-.5V8H0v2a2 2 0 0 0 2 2h2v-1.5ZM8 12v-1.5h2a.5.5 0 0 0 .5-.5V8H12v2a2 2 0 0 1-2 2H8Zm2-12a2 2 0 0 1 2 2v2h-1.5V2a.5.5 0 0 0-.5-.5H8V0h2Z\" \/>\n\t\t\t<\/svg>\n\t\t<\/button><figcaption class=\"wp-element-caption\"><em>&#8220;Genes4Mars&#8221; presentation at the AMADEE-24 Science Workshop at Vega Observatory and Haus der Natur in Salzburg (c) OeWF<\/em><\/figcaption><\/figure>\n<\/div>\n\n\n<p class=\"has-background wp-block-paragraph\" style=\"background-color:#efefef\"><strong>Source: <\/strong>Gisane Khachatryan, Toma Sirunyan, Lilit Ghukasyan, Arpine Minasyan, Hovsep Ghazaryan, Andranik Chavushyan, Nina Gruber, Jelena Savic, Partha Dip Mahanta, Roksana Zakharyan, Arsen Arakelyan, <strong>&#8220;Telomere Length Dynamics in Analog Astronauts During the AMADEE-24 Mission&#8221;, <\/strong>AMADEE-24 Science Workshop Booklet 2024<br><br><em><em>\u201cGenes4Mars\u201d Project<\/em><\/em> <br><em>Institute of Molecular Biology NAS RA, Yerevan, Armenia<\/em> <br><em>Institute of Biomedicine and Pharmacy RAU, Yerevan, Armenia<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Telomeres are essential structures located at the ends of linear chromosomes in eukaryotes. In humans, they consist of short TTAGGG repeats and are associated with various proteins [ref]. They play a critical role in maintaining the structural integrity of chromosomes [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":24499,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_members_access_role":[],"_members_access_error":""},"categories":[1741,3],"tags":[1815,1814,1819,1817,1212,1818],"class_list":["post-24490","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-amadee-24","category-oewf-news","tag-amadee-24-science-workshop","tag-experiment-en","tag-genes4mars","tag-haus-der-natur-en","tag-salzburg-en-2","tag-vega-observatory"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.0 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>AMADEE-24 Science Series: Telomere Length Dynamics in Analog Astronauts (Genes4Mars) - Austrian Space Forum (OeWF)<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/oewf.org\/en\/2024\/12\/amadee-24-science-series-telomere-length-dynamics-in-analog-astronauts-genes4mars\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"AMADEE-24 Science Series: Telomere Length Dynamics in Analog Astronauts (Genes4Mars) - Austrian Space Forum (OeWF)\" \/>\n<meta property=\"og:description\" content=\"Telomeres are essential structures located at the ends of linear chromosomes in eukaryotes. In humans, they consist of short TTAGGG repeats and are associated with various proteins [ref]. They play a critical role in maintaining the structural integrity of chromosomes [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/oewf.org\/en\/2024\/12\/amadee-24-science-series-telomere-length-dynamics-in-analog-astronauts-genes4mars\/\" \/>\n<meta property=\"og:site_name\" content=\"Austrian Space Forum (OeWF)\" \/>\n<meta property=\"article:published_time\" content=\"2024-12-08T17:57:14+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2024-12-17T08:47:58+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/oewf.org\/wp-content\/uploads\/2024\/12\/ebb256ca-140f-484a-8db3-6cb9ed7847e0.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"2048\" \/>\n\t<meta property=\"og:image:height\" content=\"1536\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"OeWF\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@oewf\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"OeWF\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"4 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/oewf.org\\\/en\\\/2024\\\/12\\\/amadee-24-science-series-telomere-length-dynamics-in-analog-astronauts-genes4mars\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/oewf.org\\\/en\\\/2024\\\/12\\\/amadee-24-science-series-telomere-length-dynamics-in-analog-astronauts-genes4mars\\\/\"},\"author\":{\"name\":\"OeWF\",\"@id\":\"https:\\\/\\\/oewf.org\\\/#\\\/schema\\\/person\\\/d33b1cc5e9a431b7ad8c32cefeaa4aa7\"},\"headline\":\"AMADEE-24 Science Series: Telomere Length Dynamics in Analog Astronauts (Genes4Mars)\",\"datePublished\":\"2024-12-08T17:57:14+00:00\",\"dateModified\":\"2024-12-17T08:47:58+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/oewf.org\\\/en\\\/2024\\\/12\\\/amadee-24-science-series-telomere-length-dynamics-in-analog-astronauts-genes4mars\\\/\"},\"wordCount\":487,\"image\":{\"@id\":\"https:\\\/\\\/oewf.org\\\/en\\\/2024\\\/12\\\/amadee-24-science-series-telomere-length-dynamics-in-analog-astronauts-genes4mars\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/oewf.org\\\/wp-content\\\/uploads\\\/2024\\\/12\\\/ebb256ca-140f-484a-8db3-6cb9ed7847e0.jpg\",\"keywords\":[\"AMADEE-24 Science Workshop\",\"experiment\",\"Genes4Mars\",\"Haus der Natur\",\"Salzburg\",\"Vega Observatory\"],\"articleSection\":[\"AMADEE-24\",\"OeWF News\"],\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/oewf.org\\\/en\\\/2024\\\/12\\\/amadee-24-science-series-telomere-length-dynamics-in-analog-astronauts-genes4mars\\\/\",\"url\":\"https:\\\/\\\/oewf.org\\\/en\\\/2024\\\/12\\\/amadee-24-science-series-telomere-length-dynamics-in-analog-astronauts-genes4mars\\\/\",\"name\":\"AMADEE-24 Science Series: Telomere Length Dynamics in Analog Astronauts (Genes4Mars) - Austrian Space Forum (OeWF)\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/oewf.org\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/oewf.org\\\/en\\\/2024\\\/12\\\/amadee-24-science-series-telomere-length-dynamics-in-analog-astronauts-genes4mars\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/oewf.org\\\/en\\\/2024\\\/12\\\/amadee-24-science-series-telomere-length-dynamics-in-analog-astronauts-genes4mars\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/oewf.org\\\/wp-content\\\/uploads\\\/2024\\\/12\\\/ebb256ca-140f-484a-8db3-6cb9ed7847e0.jpg\",\"datePublished\":\"2024-12-08T17:57:14+00:00\",\"dateModified\":\"2024-12-17T08:47:58+00:00\",\"author\":{\"@id\":\"https:\\\/\\\/oewf.org\\\/#\\\/schema\\\/person\\\/d33b1cc5e9a431b7ad8c32cefeaa4aa7\"},\"breadcrumb\":{\"@id\":\"https:\\\/\\\/oewf.org\\\/en\\\/2024\\\/12\\\/amadee-24-science-series-telomere-length-dynamics-in-analog-astronauts-genes4mars\\\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/oewf.org\\\/en\\\/2024\\\/12\\\/amadee-24-science-series-telomere-length-dynamics-in-analog-astronauts-genes4mars\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/oewf.org\\\/en\\\/2024\\\/12\\\/amadee-24-science-series-telomere-length-dynamics-in-analog-astronauts-genes4mars\\\/#primaryimage\",\"url\":\"https:\\\/\\\/oewf.org\\\/wp-content\\\/uploads\\\/2024\\\/12\\\/ebb256ca-140f-484a-8db3-6cb9ed7847e0.jpg\",\"contentUrl\":\"https:\\\/\\\/oewf.org\\\/wp-content\\\/uploads\\\/2024\\\/12\\\/ebb256ca-140f-484a-8db3-6cb9ed7847e0.jpg\",\"width\":2048,\"height\":1536},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/oewf.org\\\/en\\\/2024\\\/12\\\/amadee-24-science-series-telomere-length-dynamics-in-analog-astronauts-genes4mars\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Startseite\",\"item\":\"https:\\\/\\\/oewf.org\\\/en\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"AMADEE-24 Science Series: Telomere Length Dynamics in Analog Astronauts (Genes4Mars)\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/oewf.org\\\/#website\",\"url\":\"https:\\\/\\\/oewf.org\\\/\",\"name\":\"Austrian Space Forum (OeWF)\",\"description\":\"\u00d6sterreichisches Weltraum Forum Austrian Space Forum\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/oewf.org\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"https:\\\/\\\/oewf.org\\\/#\\\/schema\\\/person\\\/d33b1cc5e9a431b7ad8c32cefeaa4aa7\",\"name\":\"OeWF\",\"sameAs\":[\"https:\\\/\\\/www.oewf.org\",\"https:\\\/\\\/x.com\\\/oewf\"],\"url\":\"https:\\\/\\\/oewf.org\\\/en\\\/author\\\/oewf\\\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"AMADEE-24 Science Series: Telomere Length Dynamics in Analog Astronauts (Genes4Mars) - Austrian Space Forum (OeWF)","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/oewf.org\/en\/2024\/12\/amadee-24-science-series-telomere-length-dynamics-in-analog-astronauts-genes4mars\/","og_locale":"en_US","og_type":"article","og_title":"AMADEE-24 Science Series: Telomere Length Dynamics in Analog Astronauts (Genes4Mars) - Austrian Space Forum (OeWF)","og_description":"Telomeres are essential structures located at the ends of linear chromosomes in eukaryotes. In humans, they consist of short TTAGGG repeats and are associated with various proteins [ref]. They play a critical role in maintaining the structural integrity of chromosomes [&hellip;]","og_url":"https:\/\/oewf.org\/en\/2024\/12\/amadee-24-science-series-telomere-length-dynamics-in-analog-astronauts-genes4mars\/","og_site_name":"Austrian Space Forum (OeWF)","article_published_time":"2024-12-08T17:57:14+00:00","article_modified_time":"2024-12-17T08:47:58+00:00","og_image":[{"width":2048,"height":1536,"url":"https:\/\/oewf.org\/wp-content\/uploads\/2024\/12\/ebb256ca-140f-484a-8db3-6cb9ed7847e0.jpg","type":"image\/jpeg"}],"author":"OeWF","twitter_card":"summary_large_image","twitter_creator":"@oewf","twitter_misc":{"Written by":"OeWF","Est. reading time":"4 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/oewf.org\/en\/2024\/12\/amadee-24-science-series-telomere-length-dynamics-in-analog-astronauts-genes4mars\/#article","isPartOf":{"@id":"https:\/\/oewf.org\/en\/2024\/12\/amadee-24-science-series-telomere-length-dynamics-in-analog-astronauts-genes4mars\/"},"author":{"name":"OeWF","@id":"https:\/\/oewf.org\/#\/schema\/person\/d33b1cc5e9a431b7ad8c32cefeaa4aa7"},"headline":"AMADEE-24 Science Series: Telomere Length Dynamics in Analog Astronauts (Genes4Mars)","datePublished":"2024-12-08T17:57:14+00:00","dateModified":"2024-12-17T08:47:58+00:00","mainEntityOfPage":{"@id":"https:\/\/oewf.org\/en\/2024\/12\/amadee-24-science-series-telomere-length-dynamics-in-analog-astronauts-genes4mars\/"},"wordCount":487,"image":{"@id":"https:\/\/oewf.org\/en\/2024\/12\/amadee-24-science-series-telomere-length-dynamics-in-analog-astronauts-genes4mars\/#primaryimage"},"thumbnailUrl":"https:\/\/oewf.org\/wp-content\/uploads\/2024\/12\/ebb256ca-140f-484a-8db3-6cb9ed7847e0.jpg","keywords":["AMADEE-24 Science Workshop","experiment","Genes4Mars","Haus der Natur","Salzburg","Vega Observatory"],"articleSection":["AMADEE-24","OeWF News"],"inLanguage":"en-US"},{"@type":"WebPage","@id":"https:\/\/oewf.org\/en\/2024\/12\/amadee-24-science-series-telomere-length-dynamics-in-analog-astronauts-genes4mars\/","url":"https:\/\/oewf.org\/en\/2024\/12\/amadee-24-science-series-telomere-length-dynamics-in-analog-astronauts-genes4mars\/","name":"AMADEE-24 Science Series: Telomere Length Dynamics in Analog Astronauts (Genes4Mars) - Austrian Space Forum (OeWF)","isPartOf":{"@id":"https:\/\/oewf.org\/#website"},"primaryImageOfPage":{"@id":"https:\/\/oewf.org\/en\/2024\/12\/amadee-24-science-series-telomere-length-dynamics-in-analog-astronauts-genes4mars\/#primaryimage"},"image":{"@id":"https:\/\/oewf.org\/en\/2024\/12\/amadee-24-science-series-telomere-length-dynamics-in-analog-astronauts-genes4mars\/#primaryimage"},"thumbnailUrl":"https:\/\/oewf.org\/wp-content\/uploads\/2024\/12\/ebb256ca-140f-484a-8db3-6cb9ed7847e0.jpg","datePublished":"2024-12-08T17:57:14+00:00","dateModified":"2024-12-17T08:47:58+00:00","author":{"@id":"https:\/\/oewf.org\/#\/schema\/person\/d33b1cc5e9a431b7ad8c32cefeaa4aa7"},"breadcrumb":{"@id":"https:\/\/oewf.org\/en\/2024\/12\/amadee-24-science-series-telomere-length-dynamics-in-analog-astronauts-genes4mars\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/oewf.org\/en\/2024\/12\/amadee-24-science-series-telomere-length-dynamics-in-analog-astronauts-genes4mars\/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/oewf.org\/en\/2024\/12\/amadee-24-science-series-telomere-length-dynamics-in-analog-astronauts-genes4mars\/#primaryimage","url":"https:\/\/oewf.org\/wp-content\/uploads\/2024\/12\/ebb256ca-140f-484a-8db3-6cb9ed7847e0.jpg","contentUrl":"https:\/\/oewf.org\/wp-content\/uploads\/2024\/12\/ebb256ca-140f-484a-8db3-6cb9ed7847e0.jpg","width":2048,"height":1536},{"@type":"BreadcrumbList","@id":"https:\/\/oewf.org\/en\/2024\/12\/amadee-24-science-series-telomere-length-dynamics-in-analog-astronauts-genes4mars\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Startseite","item":"https:\/\/oewf.org\/en\/"},{"@type":"ListItem","position":2,"name":"AMADEE-24 Science Series: Telomere Length Dynamics in Analog Astronauts (Genes4Mars)"}]},{"@type":"WebSite","@id":"https:\/\/oewf.org\/#website","url":"https:\/\/oewf.org\/","name":"Austrian Space Forum (OeWF)","description":"\u00d6sterreichisches Weltraum Forum Austrian Space Forum","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/oewf.org\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Person","@id":"https:\/\/oewf.org\/#\/schema\/person\/d33b1cc5e9a431b7ad8c32cefeaa4aa7","name":"OeWF","sameAs":["https:\/\/www.oewf.org","https:\/\/x.com\/oewf"],"url":"https:\/\/oewf.org\/en\/author\/oewf\/"}]}},"_links":{"self":[{"href":"https:\/\/oewf.org\/en\/wp-json\/wp\/v2\/posts\/24490","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/oewf.org\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/oewf.org\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/oewf.org\/en\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/oewf.org\/en\/wp-json\/wp\/v2\/comments?post=24490"}],"version-history":[{"count":0,"href":"https:\/\/oewf.org\/en\/wp-json\/wp\/v2\/posts\/24490\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/oewf.org\/en\/wp-json\/wp\/v2\/media\/24499"}],"wp:attachment":[{"href":"https:\/\/oewf.org\/en\/wp-json\/wp\/v2\/media?parent=24490"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/oewf.org\/en\/wp-json\/wp\/v2\/categories?post=24490"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/oewf.org\/en\/wp-json\/wp\/v2\/tags?post=24490"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}